Pentylenetetrazole preconditioning attenuates severity of status epilepticus induced by lithium-pilocarpine in male rats: evaluation of opioid/NMDA receptors and nitric oxide pathway.

Faezeh EslamiMaryam ShayanArash AmanlouNastaran RahimiPegah DejbanAhmad Reza Dehpour

Published in: Pharmacological reports : PR (2022)

Therefore, PTZ preconditioning generates endogenous protection against SE, possibly through targeting opioid/NMDA receptors and NO signaling transduction in the animal model of lithium-pilocarpine-induced SE.

Keyphrases

nitric oxide
chronic pain
pain management
ischemia reperfusion injury
solid state
cerebral ischemia
high glucose
diabetic rats
hydrogen peroxide
cancer therapy
drug induced
nitric oxide synthase
oxidative stress
endothelial cells