Radiation-Associated Lymphopenia and Outcomes of Patients with Unresectable Hepatocellular Carcinoma Treated with Radiotherapy.

Brian Sandeep DeSweet Ping NgAmy Y LiuSantiago AvilaRanda TaoEmma B HollidayZachary BrownleeAhmed KasebSunyoung LeeKanwal RaghavJean-Nicolas VautheyBruce D MinskyJoseph M HermanPrajnan DasGrace L SmithCullen M TaniguchiSunil KrishnanChristopher H CraneClemens GrassbergerTheodore S HongSteven H LinAlbert C KoongRadhe MohanEugene Jon Koay

Published in: Journal of hepatocellular carcinoma (2021)

Grade 3 or higher lymphopenia may be associated with poorer outcomes in patients receiving RT for HCC. Protons may mitigate lymphopenia compared with photons, potentially due to reduced dose exposure of sites of lymphopoiesis.

Keyphrases

locally advanced
radiation induced
radiation therapy
squamous cell carcinoma
metabolic syndrome
rectal cancer
newly diagnosed