Missing prognostic value of soluble PD-1, PD-L1 and PD-L2 in lung cancer patients undergoing chemotherapy - A CEPAC-TDM biomarker substudy.
Kimberly GeigerMarkus JoergerMax RoesslerKarina HettwerChristoph RitterKirsten SimonSteffen UhligStefan HoldenriederPublished in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2024)
Neither soluble PD-1, PD-L1 nor PD-L2 did provide clinical utility for predicting response to chemotherapy and prognosis. Studies on the relevance of PD markers in ICI therapies are warranted.