The occurrence of gastric cancer has been associated with an increased risk of lobular breast tumors in a subset of patients harboring selected germline mutations. Among all, the germline alteration of the gene coding for E-Cadherin (CDH1) was associated with an increased risk of gastric cancer diffuse-histotype and lobular breast cancer. However, the risk assessment of breast neoplasms and the role of multiple prophylactic procedures in these patients has never been systematically addressed. In addition, the performance of the common screening procedures for lobular breast cancer like mammography is suboptimal. Therefore, recalling the need for a better articulation of the patient-centered strategies of surveillance for individuals with germline CDH1 and other similar alterations, to offer comprehensive approaches for prevention, early diagnosis, and treatment. Accordingly, this chapter aims to discuss the value and the role of integrated oncological care in the era of oncology sub-specializations. Additionally, it sheds light on how the harmonization across the health providers can enhance patient care in this setting.
Keyphrases
- risk assessment
- end stage renal disease
- palliative care
- healthcare
- ejection fraction
- public health
- dna repair
- peritoneal dialysis
- prognostic factors
- prostate cancer
- magnetic resonance
- oxidative stress
- quality improvement
- transcription factor
- heavy metals
- rectal cancer
- dna methylation
- young adults
- contrast enhanced
- high grade
- health information