Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells.

Won Chan HwangDong Woo KangYoura KangYounghoon JangJung-Ae KimDo Sik Min

Published in: Biological research (2020)

These findings provide further insight into elucidating the advantages of combination therapy with HDAC and PLD2 inhibitors over single-agent strategies for the treatment of cancer.

Keyphrases

combination therapy
histone deacetylase
cell death
breast cancer cells
papillary thyroid
high glucose
diabetic rats
squamous cell
drug induced
lymph node metastasis
young adults
cell cycle arrest
childhood cancer
smoking cessation