Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8.
Federico OldoniKevin BassJulia KozlitinaHannah HudsonLisa M ShihanianViktoria GusarovaJonathan C CohenHelen H HobbsPublished in: The Journal of clinical endocrinology and metabolism (2021)
A8 levels were strongly associated with indices of glucose and TG metabolism, but the lack of association of genetic variants at the A8 locus that impact A8 levels with these parameters indicates that differences in A8 levels are not causally related to the associated metabolic phenotypes.