Proton pump inhibitors are associated with incident type 2 diabetes mellitus in a prospective population-based cohort study.

Petra CzarniakFariba AhmadizarJeff HughesRichard ParsonsMaryam KavousiMohammad IkramBruno H Stricker

Published in: British journal of clinical pharmacology (2021)

New users of PPIs during follow-up had a significantly higher dose-dependent risk of incident diabetes. We suggest vigilance regarding their potential adverse effect on glucose homeostasis.

Keyphrases

cardiovascular disease
glycemic control
type diabetes
blood glucose
cardiovascular risk factors
human health
emergency department
insulin resistance
risk assessment
adipose tissue
weight loss
climate change