PBRM1 presents a potential prognostic marker and therapeutic target in duodenal papillary carcinoma.
Xujun HeJi XuNan NiuGuoxi XuHonglin ZhuZhengchuang LiuYiping MouZhengyuan QianHuiju WangJunfeng HuTonghui MaJie MaHouquan TaoPublished in: Clinical and translational medicine (2022)
Our findings define a novel molecular subgroup of PBRM1-inactivating mutations in DPC. PBRM1 play an important role in DPC progression and may serve as a potential therapeutic target and prognostic indicator.
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