Diversely evolved xibalbin variants from remipede venom inhibit potassium channels and activate PKA-II and Erk1/2 signaling.

Ernesto Lopes Pinheiro-JuniorEhsan AlirahimiSteve PeigneurJörg IsenseeSusanne SchiffmannPelin ErkocRobert FürstAndreas VilcinskasTobias SennonerIvan KoludarovBenjamin-Florian HempelJan TytgatTim HuchoBjörn Marcus von Reumont

Published in: BMC biology (2024)

. Our study is an important cornerstone for future studies to untangle the origin and function of these enigmatic proteins as important components of remipede but also other pancrustacean and arthropod venoms.

Keyphrases

signaling pathway
cell proliferation
copy number
current status
dna methylation
case control
genome wide