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Diversely evolved xibalbin variants from remipede venom inhibit potassium channels and activate PKA-II and Erk1/2 signaling.

Ernesto Lopes Pinheiro-JuniorEhsan AlirahimiSteve PeigneurJörg IsenseeSusanne SchiffmannPelin ErkocRobert FürstAndreas VilcinskasTobias SennonerIvan KoludarovBenjamin-Florian HempelJan TytgatTim HuchoBjörn Marcus von Reumont
Published in: BMC biology (2024)
. Our study is an important cornerstone for future studies to untangle the origin and function of these enigmatic proteins as important components of remipede but also other pancrustacean and arthropod venoms.
Keyphrases
  • signaling pathway
  • cell proliferation
  • copy number
  • current status
  • dna methylation
  • case control
  • genome wide