Artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in MPP+-treated SH-SY5Y cells.

Junqiang YanHongxia MaXiaoyi LaiJiannan WuAnran LiuJiarui HuangWenjie SunMengmeng ShenYude Zhang

Published in: Journal of biological research (Thessalonike, Greece) (2021)

Our results indicate that ART has a protective effect on MPP+-treated SH-SY5Y cells by the antioxidant, antiapoptotic activities and inhibition of autophagy. Our findings may provide new hope for the prevention and treatment of PD.

Keyphrases

oxidative stress
induced apoptosis
endoplasmic reticulum stress
cell cycle arrest
cell death
signaling pathway
ischemia reperfusion injury
diabetic rats
dna damage
hiv infected
anti inflammatory
plasmodium falciparum
heat stress