The value of spot urinary creatinine as a marker of muscle wasting in patients with new-onset or worsening heart failure.
Paloma PandhiKoen W StrengStefan D AnkerJohn G F ClelandKevin DammanKenneth DicksteinPierpaolo PellicoriChim C LangLeong L NgNilesh J SamaniFaiez ZannadMarco MetraPatrick RossignolGerasimos FilippatosDirk J van VeldhuisenCarolyn S P LamJozine M Ter MaatenPublished in: Journal of cachexia, sarcopenia and muscle (2021)
Lower spot urinary creatinine is associated with smaller body dimensions, renal dysfunction, and more severe HF in patients with new-onset/WHF. Additionally, lower spot urinary creatinine is associated with an increased risk of weight loss and a poorer exercise capacity/quality of life. Urinary creatinine could therefore be a novel, easily obtainable marker to assess (risk of) muscle wasting in HF patients.
Keyphrases
- uric acid
- heart failure
- weight loss
- end stage renal disease
- skeletal muscle
- chronic kidney disease
- acute heart failure
- ejection fraction
- bariatric surgery
- oxidative stress
- prognostic factors
- high intensity
- early onset
- adipose tissue
- roux en y gastric bypass
- atrial fibrillation
- body mass index
- resistance training
- drug induced
- obese patients