Identifying placental metabolic biomarkers of preterm birth using nuclear magnetic resonance of intact tissue samples.

Grace V MercerDarcie StapletonCatherine BarrettLauren C M RingerStacy LambeAmanda CritchGabrielle NewmanAshley PelleyRajshree Ghosh BiswasWilliam WolffFlavio Crizostomo KockRonald SoongAndré J SimpsonLindsay S Cahill

Published in: Placenta (2023)

PTB is associated with significant alterations in placental metabolism. This study helps improve our understanding of the etiology of PTB. It also highlights the potential for small molecule metabolites to serve as placental metabolic biomarkers to aid in the prediction and diagnosis of PTB. The results can be translated to clinical use via in utero magnetic resonance spectroscopy.

Keyphrases

preterm birth
small molecule
magnetic resonance
low birth weight
gestational age
ms ms
computed tomography