Development of two recombinant vaccines against Clostridioides difficile infection and immunogenicity in pregnant sows and neonatal piglets.

Carolina P RamosWilliane F SiqueiraLaila A VianaJoão L R CunhaRicardo T FujiwaraVictor S AmaranteThayanne G V SouzaRodrigo O S Silva

Published in: Anaerobe (2024)

The synthesized recombinant proteins were capable of inducing antibody titers against C. difficile toxins A and B in sows, and were passively transferred to piglets through colostrum.

Keyphrases

clostridium difficile
cell free
human milk
preterm infants
low birth weight