Comment on "Bulk Nanobubbles or Not Nanobubbles: That is the Question".

In a recent article, Jadhav and Barigou ( Langmuir 2020, 36 (7), 1699-1708) investigated the question of the existence of stable bulk nanobubbles in water generated by hydrodynamic cavitation, ultrasound cavitation, and the addition of an organic compound (namely, ethanol) to water. They firmly conclude that these procedures result in stable bulk nanobubbles. However, a number of previous works documented that the nanoentities observed in water upon such procedures are not nanobubbles. Here, we analyze work of Jadhav and Barigou and show that conclusions regarding the nanobubble nature of the nanoentities are incorrect and are due to the choice of experimental techniques with weak sensitivity, methodical issues in the use of otherwise proper experimental techniques, and ambiguous outcomes of the rest of experiments.