Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity.
Yu-Jui KungBrandon LamSsu-Hsueh TsengAlana MacDonaldHsin-Fang TuSuyang WangJohn LinYa Chea TsaiT C WuChien Fu HungPublished in: Journal of biomedical science (2022)
These findings highlight the ability of Salmonella + Alb-IL2 to serve as a novel therapeutic approach to induce T cell-mediated antitumor immunity and exert long-term tumor control in a murine model of cancer.