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Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity.

Yu-Jui KungBrandon LamSsu-Hsueh TsengAlana MacDonaldHsin-Fang TuSuyang WangJohn LinYa Chea TsaiT C WuChien Fu Hung
Published in: Journal of biomedical science (2022)
These findings highlight the ability of Salmonella + Alb-IL2 to serve as a novel therapeutic approach to induce T cell-mediated antitumor immunity and exert long-term tumor control in a murine model of cancer.
Keyphrases
  • escherichia coli
  • listeria monocytogenes
  • papillary thyroid
  • squamous cell
  • squamous cell carcinoma
  • lymph node metastasis