Intestinal Microbiome Changes in Fecal Microbiota Transplant (FMT) vs. FMT Enriched with Lactobacillus in the Treatment of Recurrent Clostridioides difficile Infection.
Elvira Garza-GonzálezSoraya Mendoza-OlazaránMaría Del Rayo Morfin-OteroAndrea Ramírez-FontesPatricia Rodríguez-ZuluetaSamantha Flores-TreviñoPaola Bocanegra-IbariasHéctor Maldonado-GarzaAdrián Camacho-OrtízPublished in: Canadian journal of gastroenterology & hepatology (2019)
Fecal microbiota transplant by capsules was clinically and genomically similar between traditional FMT and enriched FMT with Lactobacillus spp. Restoration of bacterial diversity and resolution of dysbiosis at days 7 and 28 were observed. Patients with a first episode of recurrence treated with FMT had an excellent response without severe adverse events; FMT should be considered as an early treatment during R-CDI.