Evaluation of Age and Sex-Related Metabolic Changes in Healthy Subjects: An Italian Brain 18F-FDG PET Study.
Michela AlloccaFlavia LinguantiMaria Lucia CalcagniAngelina CistaroValeria GaudieriUgo Paolo GuerraSilvia MorbelliFlavio NobiliSabina PappatàStelvio SestiniDuccio VolterraniValentina Bertinull For The Neurology Study Group Of The Italian Association Of Nuclear MedicinePublished in: Journal of clinical medicine (2021)
this study demonstrated an age-related metabolic reduction in frontal lobes and in some parieto-temporal areas more evident in females. Results suggested pons as the most appropriate normalization reference. Knowledge of age- and sex-related cerebral metabolic changes is critical to correctly interpreting brain 18F-FDG PET imaging.