The effect of carpal tunnel release on health-related quality of life of 2346 patients over a 5-year period.
Justin D PostmaBryson R KemlerPublished in: The Journal of hand surgery, European volume (2021)
In this prospective cohort study, the health-related quality of life (HRQoL) from a societal perspective of carpal tunnel syndrome (CTS) patients was determined and compared with other diseases. In addition, the effect of carpal tunnel release (CTR) was analysed 6 weeks postoperatively with regard to mean EQ-5D index value improvement, side-effects of surgery and cost per quality adjusted life year (QALY) gained. We found a baseline mean EQ-5D index value of 0.75 (SD: 0.23), comparable with values seen in other disease like breast cancer, diabetes and asthma. Furthermore, we found that CTR improved HRQoL substantially 6 weeks postoperatively (mean + 0.12, SD: 0.22) and significantly reduced symptom reporting (mean -52%, SD: 53) with a cost per QALY gained of €396.05. In conclusion, CTS has a comparable impact on quality of life as compared with other diseases, and CTR has the potential to substantially improve patient's HRQoL at a fairly modest cost.Level of evidence: III.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- cardiovascular disease
- peritoneal dialysis
- prognostic factors
- chronic obstructive pulmonary disease
- minimally invasive
- risk assessment
- quality improvement
- cystic fibrosis
- acute coronary syndrome
- insulin resistance
- patient reported
- coronary artery bypass
- lung function
- adverse drug
- weight loss
- preterm birth