De-escalation strategies in patients with acute coronary syndrome: a step towards precision medicine.

Felice GragnanoAntonio CapolongoFabrizia TerraccianoVincenzo De SioPasquale MaddalunaFabio FimianiElisabetta MoscarellaArturo CesaroRocco A MontoneRoberto BiancoDanilo LisiMario Massimo MensorioAngela AnnecchiaricoPaolo Calabrò

Published in: Expert review of cardiovascular therapy (2023)

Among patients with ACS, guided and unguided de-escalation strategies are safe and effective for secondary cardiovascular prevention. Although the implementation of genetic and platelet function tests is of interest for treatment personalization, the routine use of guided de-escalation strategies seems impractical. In this context, unguided de-escalation approaches appear more attractive, convenient, and suitable for contemporary practice.

Keyphrases

open label
primary care
healthcare
acute coronary syndrome
quality improvement
clinical trial
genome wide
dna methylation
study protocol
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