All High-Grade Ta Tumors Should Be Classified as High Risk: Bacillus Calmette-Guérin Response in High-Grade Ta Tumors.
Kelly K BreePatrick J HensleyNiyati LoboNathan A BrooksGraciela M Nogueras-GonzalezCharles C GuoNeema NavaiH Barton GrossmanColin P DinneyAshish M KamatPublished in: The Journal of urology (2022)
All HG Ta tumors, regardless of EAU risk stratification, have inferior response to BCG and increased rates of progression compared to IR LG Ta tumors. EAU clinical risk factors did not improve prediction of oncologic outcomes among HG Ta patients who received adequate BCG. These data support consideration of all HG tumors as high risk.