Glymphatic dysfunction in isolated REM sleep behavior disorder.
Dong Ah LeeHo-Joon LeeKang Min ParkPublished in: Acta neurologica Scandinavica (2021)
The DTI-ALPS index was significantly lower in patients with iRBD than in healthy controls, indicating the presence of glymphatic-system dysfunction in patients with iRBD. Our study also suggests that the DTI-ALPS index could serve as a biomarker for evaluating glymphatic-system function in neurological disorders.