Prior antiplatelet therapy in patients undergoing endovascular treatment for acute ischemic stroke: Results from the MR CLEAN Registry.
Rob A van de GraafSanne M ZinkstokVicky ChalosRobert-Jan B GoldhoornCharles Blm MajoieRobert J van OostenbruggeAad van der LugtDiederik Wj DippelYvo Bwem RoosHester F LingsmaAdriaan Cgm van EsBob Roozenbeeknull nullPublished in: International journal of stroke : official journal of the International Stroke Society (2020)
We found no evidence of an association of prior antiplatelet therapy with the risk of symptomatic intracranial hemorrhage after endovascular treatment, nor on functional outcome, reperfusion, or mortality. A substantial beneficial or detrimental effect of antiplatelet therapy on clinical outcome cannot be excluded. A randomized clinical trial comparing antiplatelet therapy versus no antiplatelet therapy is needed.
Keyphrases
- antiplatelet therapy
- endovascular treatment
- acute coronary syndrome
- percutaneous coronary intervention
- acute ischemic stroke
- patients undergoing
- acute myocardial infarction
- coronary artery disease
- magnetic resonance
- magnetic resonance imaging
- type diabetes
- computed tomography
- heart failure
- cardiovascular disease
- contrast enhanced
- blood brain barrier
- optic nerve