Subtle immunodeficiencies in nodular-bronchiectatic Mycobacterium avium complex lung disease.
Mariolina BrunoSanne M H ZweijpfenningJeske VerhoevenMartin J BoereeMihai G NeteaFrank L van de VeerdonkJakko van IngenWouter HoefslootPublished in: ERJ open research (2020)
Patients with nodular-bronchiectatic MAC lung disease have dysregulated adaptive immunity with defective IL-17 and IFN-γ production, and IL-10 overproduction. This suggests a role for adjunctive immunomodulatory treatments. https://bit.ly/33AALwx.