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Role of vertebral corner inflammation and fat deposition on MRI on syndesmophyte development detected on whole spine low-dose CT scan in radiographic axial spondyloarthritis.

Rosalinde Anne StalXenofon BaraliakosDésirée Mfm van der HeijdeFloris A van GaalenJosef S SmolenRosaline van den BergMonique ReijnierseJüergen BraunRobert B M LandeweAlexandre Sepriano
Published in: RMD open (2022)
VCI and VCFD were positively associated with syndesmophyte development. This has been shown for the first time for syndesmophytes detected on ldCT and also in the thoracic spine. However, almost half of all bone formation occurred in corners without VCI or VCFD, suggesting the presence of these lesions in yearly MRIs does not fully clarify the development of syndesmophytes.
Keyphrases
  • low dose
  • computed tomography
  • oxidative stress
  • contrast enhanced
  • adipose tissue
  • spinal cord
  • rheumatoid arthritis
  • bone mineral density
  • ankylosing spondylitis
  • positron emission tomography
  • postmenopausal women