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[Mitochondrial dysfunction].

M V Putilina
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2022)
Hypoergos-energy deficiency, i.e., a mismatch between the body's (tissue, organ, cell) need for energy and the limited amount of macroergs (ATP) that can currently be used to maintain the structural integrity and functional activity of a tissue or organ. The main role in the development of hypoergoses is played by damage to mitochondria, therefore, in recent years, this term has been replaced by mitochondrial dysfunction. Over the past 50 years, drugs have been actively studied and developed that have the ability to influence mitochondrial disorders, both primary and secondary mitochondrial diseases. In this context, Cytochrome C, an original antioxidant/antihypoxant with a dual mechanism of action, deserves attention.
Keyphrases
  • oxidative stress
  • single cell
  • working memory
  • preterm infants
  • cell death
  • mesenchymal stem cells
  • gestational age
  • stem cells
  • endoplasmic reticulum
  • bone marrow
  • preterm birth