Fe3O4@Polydopamine-Labeled MSCs Targeting the Spinal Cord to Treat Neuropathic Pain Under the Guidance of a Magnetic Field.

Meichen LiuWeijia YuFuqiang ZhangTe LiuKai LiMeng LinYing WangGuoqing ZhaoJinlan Jiang

Published in: International journal of nanomedicine (2021)

Fe3O4@PDA-labeled MSCs showed better homing to the spinal cord under magnetic field guidance. Moreover, they inhibited microglial and astrocyte activation, as well as played an early and continuous role in neuropathic pain treatment.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
mesenchymal stem cells
pet imaging
umbilical cord
combination therapy
computed tomography
lipopolysaccharide induced
pet ct