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A phenotypic screening bioassay for Escherichia coli stress and antibiotic responses based on Fourier-transform infrared (FTIR) spectroscopy and multivariate analysis.

Bernardo Ribeiro da CunhaL P FonsecaC R C Calado
Published in: Journal of applied microbiology (2019)
Highly optimized FTIRS bioassay parameters are vital in capturing whole-spectra metabolic signatures that can be used for satisfactory and reproducible phenotypic screening of stress and antibiotic responses.
Keyphrases
  • escherichia coli
  • stress induced
  • high resolution
  • single molecule
  • genome wide
  • data analysis
  • dna methylation
  • cystic fibrosis