The Impacts of Obstructive Sleep Apnea Severity on Brain White Matter Integrity and Cognitive Functions in Children: A Diffusion Tensor Imaging Study.

Lin MeiXiaodan LiShengcai WangRun SiTingting JiZhifei XuYun PengYue LiuHongbin LiJie ZhangYongli GuoJinghong TianGuifei ZhouHuifang HuangJun TaiJiangang LiuXin Ni

Published in: Nature and science of sleep (2021)

Decreased baseline SpO2, WM impairment, and intelligence decline were all observed only for SG, but not for MG, implying an associated relationship among decreased SpO2, WM impairment and WM impairment. Thus, for SG, additional assessments of brain damage and cognitive function decline are needed for prognostic evaluation of OSA.

Keyphrases

white matter
obstructive sleep apnea
multiple sclerosis
positive airway pressure
resting state
young adults
oxidative stress
functional connectivity
blood brain barrier