Stopping anti-tumour necrosis factor therapy in patients with perianal Crohn's disease.
Wing Yan Joyce MakWhitney TangTerry Cheuk Fung YipZhi Hua RanShu Chen WeiVineet AhujaSudheer KumarWai-Keung LeungIda HilmiJulajak LimsrivilaiSatimai AniwanBelsy C Y LamKam Hon ChanKa Man NgChi Man LeungMichael K K LiFu Hang LoAlex Shun Fung SzeSteven Woon Choy TsangAric J HuiJuanda Leo HartonoWilliam K K WuPublished in: Alimentary pharmacology & therapeutics (2019)
More than half of the perianal CD patients developed relapse after stopping anti-TNF therapy. Most regained response after resuming anti-TNF. However, more than one-fourth of the perianal CD patients with relapse required defunctioning surgery. Radiological assessment before stopping anti-TNF is crucial in perianal CD.