Bladder tumor ILC1s undergo Th17-like differentiation in human bladder cancer.
Neelam MukherjeeNiannian JiXi TanChun-Lin LinEmily RiosChun-Liang ChenTim HuangRobert S SvatekPublished in: Cancer medicine (2021)
hILC1s are increased in higher stage tumors among patients with muscle-invasive bladder cancer. These intratumoral hILC1s exhibit an exhausted phenotype and Th17-like differentiation, identifying them as potential targets for immunotherapy.