Duodenal cholinergic tuft cell number is increased in functional dyspepsia.

Xin-Yi Huang Tadayuki OshimaYasutada AkibaTakanori YoshimotoJunji ChenMasato TakiToshihiko TomitaHirokazu FukuiJonathan D KaunitzHiroto Miwa

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2022)

Cholinergic tuft cell density was higher in the duodenum of patients with FD and significantly correlated with eosinophil density. Further studies are needed to investigate the pathophysiological significance of tuft cells in FD and may provide valuable clues to the pathophysiology of FD.

Keyphrases

single cell
cell therapy
induced apoptosis
stem cells
helicobacter pylori infection
cell cycle arrest
oxidative stress
cell death
mesenchymal stem cells
helicobacter pylori
endoplasmic reticulum stress