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mycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging data.

Christian Carsten SachsJoachim KoepffWolfgang WiechertAlexander GrünbergerKatharina Nöh
Published in: BMC bioinformatics (2019)
mycelyso is a well-documented, platform-independent open source toolkit for the automated end-to-end analysis of Streptomyces image stacks. The batch-analysis mode facilitates the rapid and reproducible processing of large microfluidic screenings, and easy extraction of morphological parameters. The objective evaluation of image stacks is possible by reproducible evaluation workflows, useful to unravel correlations between morphological, molecular and process parameters at the hyphae- and mycelium-levels with statistical power.
Keyphrases
  • high throughput
  • deep learning
  • single cell
  • high resolution
  • electronic health record
  • machine learning
  • big data
  • single molecule
  • data analysis
  • label free