Family environment and polygenic risk in the bipolar high-risk context.

Emma K StappJanice M FullertonRashelle J MusciPeter P ZandiMelvin G McInnisPhilip B MitchellLeslie A HulvershornNeera GhaziuddinGloria RobertsAlessandra G FerreraJohn I NurnbergerHolly C Wilcox

Published in: JCPP advances (2023)

The data suggest that the relationship of BD-PRS and offspring liability for BD differed between well-functioning versus high-conflict FE, potentially in line with a multifactorial liability threshold model and supporting future study of and interventions improving family dynamics.

Keyphrases

physical activity
high fat diet
current status
metabolic syndrome