Downregulation of cholesteryl ester transfer protein by glucocorticoids: a randomised study on HDL.
Jorien Werumeus BuningLidya G DimovaFrank G PertonUwe J F TietgeAndré P van BeekRobin P F DullaartPublished in: European journal of clinical investigation (2017)
Glucocorticoids downregulate CETP gene expression in a human macrophage cell system. In line, a higher glucocorticoid replacement dose decreases plasma CETP activity in patients, thereby contributing to higher HDL cholesterol and an increase in estimated HDL size.