Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification Among Patients With Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-income Countries.

Kathryn DupnikVanessa R RiveraNancy DorvilYanique DuffusHanane AkbarnejadYipeng GaoJingyi LiuAlexandra ApollonEmelyne DumontCynthia RivierePatrice SevereKerlyne LavoileMaria Alejandra Duran MendicutiSamuel PierreVanessa RouzierKathleen Frances WalshAnthony L ByrnePatrice JosephPierre-Yves CremieuxJean William PapeSerena P Koenig

Published in: Open forum infectious diseases (2024)

CRP concentrations can be used to improve TB risk stratification, facilitating same-day decisions about ART initiation. Depending on the CRP threshold, one-quarter to two-thirds of patients could be eligible for same-day ART, with a reduction of 3- to 20-fold in the proportion with untreated TB, compared with a strategy of same-day ART while awaiting TB test results.

Keyphrases

mycobacterium tuberculosis
hiv infected
antiretroviral therapy
end stage renal disease
hiv aids
human immunodeficiency virus
ejection fraction
hiv positive
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
hiv testing
risk assessment
depressive symptoms
human health