Risk Stratification Tools to Aid Decisions on Adjuvant Chemotherapy Usage in Resected Soft Tissue Sarcomas: A Ten-Year Review of an Irish Sarcoma Center Experience.
Catherine S WeadickCaitriona GogginRachel J KeoghJake F MurphyLinda FeeleyMichael W BennettSeamus O'ReillyH Paul RedmondJason KellyDeirdre O'MahonySinead NoonanA James P CloverRichard M BamburyPublished in: World journal of oncology (2024)
Our cohort is representative of the broad histological subtypes expected. In our population, Sarculator score results correlate with international outcomes and higher scores were associated with increased mortality. The Sarculator was more predictive of clinical outcome than AJCC staging, and its use would lower the proportion of patients being considered for adjuvant chemotherapy thereby sparing toxicity, which is important in the setting of uncertain clinical benefit.
Keyphrases
- end stage renal disease
- soft tissue
- lymph node
- prognostic factors
- ejection fraction
- newly diagnosed
- chronic kidney disease
- oxidative stress
- risk factors
- cardiovascular events
- primary care
- high grade
- coronary artery disease
- patient reported outcomes
- cardiovascular disease
- adipose tissue
- general practice
- skeletal muscle
- weight loss