Treatment with High-Dose Prednisolone in Vigabatrin-Refractory Infantile Spasms.
Wafaa Al-ShehhiVann ChauJennifer BoydCarter SneadRohit SharmaElizabeth J DonnerCristina GoPuneet JainPublished in: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (2021)
High-dose (8 mg/kg/day) oral prednisolone resulted in sustained complete ECR (at 6 weeks) in two-thirds of the children with hypsarrhythmia or hypsarrhythmia variant on EEG with/without parentally reported IS. It was generally well tolerated and found to be safe.