Portable Device for Potentiometric Determination of Antioxidant Capacity.
Alla V IvanovaMaria G MarkinaPublished in: Sensors (Basel, Switzerland) (2023)
For the first time, a prototype of a portable device for the potentiometric determination of antioxidant capacity based on a new measurement principle is proposed. A feature of the approach is the use of an electrochemical microcell with separated spaces and two identical electrodes with immobilized reagents. An antioxidant solution is introduced into one half-cell, and the antioxidants interact with the reagents. The other half-cell contains only reagents. The potential difference between the electrodes is due to the change in the ratio of the oxidized and reduced form of the reagents, which occurs as a result of the reaction with the antioxidants in one of the half-cells and is related to their concentration. The range of linearity of the microcell with immobilized reagents is 40-4000 μM-eq, and the limit of detection is 20 μM-eq. The device was successfully tested in the analysis of standard antioxidant solutions. The recoveries were (92-113)%, and the relative standard deviation did not exceed 15%. A good correlation was found between the data obtained by the approach and the potentiometric method in a macrocell for fruit juice analysis. Pearson's coefficient for the obtained experimental data was 0.9955. The proposed portable device is promising and can be used in field conditions.
Keyphrases
- single cell
- molecularly imprinted
- oxidative stress
- ionic liquid
- cell therapy
- electronic health record
- big data
- machine learning
- gold nanoparticles
- solid phase extraction
- low cost
- deep learning
- label free
- reduced graphene oxide
- cell cycle arrest
- data analysis
- signaling pathway
- bone marrow
- magnetic resonance
- high resolution
- capillary electrophoresis