Discontinuation of oral anticoagulation in atrial fibrillation and risk of ischaemic stroke.

Luis Alberto García-RodríguezLucía Cea SorianoStine Munk HaldJesper HallasYanina BalabanovaGunnar BrobertPareen VoraMike SharmaDavid Gaist

Published in: Heart (British Cardiac Society) (2020)

Our results suggest that patients with AF who discontinue OAC therapy have a significant twofold to threefold higher risk of IS compared with those who continue therapy. Addressing OAC discontinuation could potentially result in a significant reduction in AF-attributed IS.

Keyphrases

atrial fibrillation
catheter ablation
left atrial
oral anticoagulants
left atrial appendage
direct oral anticoagulants
heart failure
stem cells
mesenchymal stem cells
bone marrow
replacement therapy
smoking cessation