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Functional stress imaging to predict abnormal coronary fractional flow reserve: the PACIFIC 2 study.

Roel S DriessenPepijn A van DiemenPieter G RaijmakersJuhani KnuutiTeemu MaaniittyStephen Richard UnderwoodEike NagelLourens F H J RobbersAhmet DemirkiranMartin B von BartheldPeter M van de VenLeonard HofstraG Aernout SomsenIgor I TulevskiRonald BoellaardAlbert C van RossumIbrahim DanadPaul Knaapen
Published in: European heart journal (2022)
In this prospective head-to-head comparative study, SPECT, PET, and MRI did not show a significantly different accuracy for diagnosing FFR defined significant CAD in patients with prior PCI and/or MI. Overall diagnostic performances, however, were discouraging and the additive value of non-invasive imaging in this high-risk population is questionable.
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