Circulating exosomal mRNA signatures for the early diagnosis of clear cell renal cell carcinoma.

Xing HeFeng TianFei GuoFangxing ZhangHuiyong ZhangJin JiLin ZhaoJingyi HeYutian XiaoLongman LiChunmeng WeiCaihong HuangYexin LiFeng ZhangBo YangHuamao YeFu-Bo Wang

Published in: BMC medicine (2022)

We established and validated novel emRNA-based signatures for the early detection of ccRCC and differential diagnosis of uncertain renal masses. These signatures could be promising and noninvasive biomarkers for ccRCC detection and thus improve the prognosis of ccRCC patients.

Keyphrases

end stage renal disease
genome wide
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
magnetic resonance imaging
dna methylation
ultrasound guided
binding protein