Inhibition of transient potential receptor vanilloid type 1 suppresses seizure susceptibility in the genetically epilepsy-prone rat.

Sue J ChoMichelle A VacaClive J MirandaProsper N'Gouemo

Published in: CNS neuroscience & therapeutics (2017)

These findings suggest that the TRPV1 channel is a promising molecular target for seizure suppression, with female GEPR-3s exhibiting higher sensitivity than male GEPR-3s.

Keyphrases

temporal lobe epilepsy
signaling pathway
oxidative stress
neuropathic pain
cerebral ischemia
human health
single molecule