Identification of Key Biomarkers and Candidate Molecules in Non-Small-Cell Lung Cancer by Integrated Bioinformatics Analysis.
Liyan YuXuemei LiangJianwei WangGuangxiang DingJinhai TangJuan XueXin HeJingxuan GeXianzhang JinZhiyi YangXianwei LiHehuan YaoHongtao YinWu LiuShengchen YinBing SunJunxiu ShengPublished in: Genetics research (2023)
The results indicated that SPP1 is a cancer promoter (oncogene), while PECAM1 and PIK3R1 are cancer suppressor genes. These genes take part in the regulation of biological activities in lung adenocarcinoma, which provides a basis for improving detection and immunotherapeutic targets for lung adenocarcinoma.