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MRI analysis of neurodevelopmental anatomy in myelomeningocele: prenatal vs postnatal repair.

A K BruzekGretchen M KollerSasidhar KarupartiK VaragurA DunbarT M FlandersM MingoK SudanaguntaKatherine H BligardAnthony O OdiboJ VrecenakA MianJ M Strahle
Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2024)
We report variations in developmental neuroanatomy in patients with MMC, including rates of CC dysgenesis, gray-matter heterotopia and additional cranial and spinal MRI findings. Compared to postnatal surgery, prenatal surgery is associated with changes to infratentorial anatomy, with minimal effect on supratentorial brain development. This information will be useful in counseling parents affected by fetal MMC and in understanding how prenatal repair of MMC affects brain development. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.
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