Yeast β-Glucan Improves Insulin Sensitivity and Hepatic Lipid Metabolism in Mice Humanized with Obese Type 2 Diabetic Gut Microbiota.
Kathleen A J MitchelsonTam T T TranEugene T DillonKlara VlckovaSabine M HarrisonAlexandra NtemiriKatie CunninghamIrene GibsonFrancis M FinucaneEibhlís M O'ConnorHelen M RochePaul W O'ToolePublished in: Molecular nutrition & food research (2022)
Hepatic metabolism is adversely affected by OBD microbiome colonization with high-fat feeding, but partially resolved by yeast β-glucan. More targeted dietary interventions that encompass the interactions between diet, gut microbiota, and host metabolism may have greater treatment efficacy.