Analysis of the risk factors of linezolid-related haematological toxicity in Chinese patients.

Ying DaiShuying JiangXiaoou ChenLu HanChunhong ZhangXu-Ben YuXiuhua Zhang

Published in: Journal of clinical pharmacy and therapeutics (2021)

Hepatic and/or renal dysfunction are the risk factors for LZD-related haematological toxicity, while the target plasma trough concentration within 8 mg/L via dose reduction could minimize the haematological toxicity induced by LZD.

Keyphrases

oxidative stress
risk factors
drug induced