Inflammatory placental lesions are specifically observed in healthy oocyte donation pregnancies with extreme fetal-maternal incompatibility.

Xuezi TianNatascha N T GoemaereLotte van der MeerenJiayi YangJohanna M KapsenbergLisa E E L O LashleyMichael EikmansMarie-Louise P van der Hoorn

Published in: Placenta (2023)

Placental inflammatory lesions are most often present in uncomplicated OD pregnancies. Immune cells that infiltrate these lesions might play an immunosuppressive role to protect OD pregnancies from complications when facing a higher extent of fetal-maternal HLA mismatching.

Keyphrases

pregnancy outcomes
gestational age
birth weight
preterm birth
oxidative stress
pregnant women
urinary tract infection