Paradoxical Increase of Stroke in Patients with Defect of High Molecular Weight Multimers of the von Willebrand Factors following Transcatheter Aortic Valve Replacement.

Kensuke MatsushitaBenjamin MarchandotAntonin TrimailleMarion KiblerJoe HegerMarilou PeillexSebastien HessLelia GrunebaumAntje ReydelMichel KindoMinh Tam HoangChisato SatoFabien De PoliPierre LeddetMickael OhanaLaurence JeselPatrick OhlmannSophie SusenOlivier Morel

Published in: Thrombosis and haemostasis (2020)

MLBCs and CT-ADP > 180 seconds were identified as predictors for ischemic stroke or TIA. The present study suggests that the defects of HMW multimers of the VWFs may contribute not only to bleeding events but also to thrombotic events.

Keyphrases

transcatheter aortic valve replacement
atrial fibrillation
aortic valve
aortic stenosis
contrast enhanced
coronary artery disease
pet ct