Targeted high mean arterial pressure aggravates cerebral hemodynamics after extracorporeal resuscitation in swine.

Yael LevyAlice HutinFanny LidourenNicolas PolgeRocio FernandezMatthias KohlhauerPierre-Louis LegerGuillaume DebatyKeith LurieLionel LamhautBijan GhalehRenaud Tissier

Published in: Critical care (London, England) (2021)

During early E-CPR, MAP target above 80 mmHg is associated with higher carotid blood flow and improved cerebral autoregulation. This pattern is inverted after ROSC with a better hemodynamic status with standard versus high-MAP.

Keyphrases

blood flow
cardiac arrest
subarachnoid hemorrhage
cardiopulmonary resuscitation
cerebral blood flow
high density
cancer therapy
drug delivery
brain injury
blood brain barrier