Serum Interleukin-23 in Polish Patients with Systemic Lupus Erythematosus: Association with Lupus Nephritis, Obesity, and Peripheral Vascular Disease.

Katarzyna FischerHanna Przepiera-BędzakMarcin SawickiAnna WaleckaIwona BrzoskoMarek Brzosko

Published in: Mediators of inflammation (2017)

IL-23 may be involved in lupus nephritis pathogenesis. Through its association with obesity and selected antiphospholipid antibodies, IL-23 might promote a hypercoagulable state contributing to atherothrombosis development in SLE patients.

Keyphrases

systemic lupus erythematosus
insulin resistance
end stage renal disease
metabolic syndrome
weight loss
type diabetes
newly diagnosed
chronic kidney disease
ejection fraction
weight gain
high fat diet induced
peritoneal dialysis
rheumatoid arthritis
disease activity
skeletal muscle
patient reported